- CAS 350-12-9
- Purity 99%
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Manufacturer supply high quality sulbentine 350-12-9 with GMP standards
- Molecular Formula: C17H18 N2 S2
- Molecular Weight: 314.475
- Vapor Pressure: 2.42E-08mmHg at 25°C
- Melting Point: 101-102°
- Boiling Point: 451.5°Cat760mmHg
- Flash Point: 226.9°C
- PSA： 63.87000
- Density: 1.28g/cm3
- LogP: 3.81330
sulbentine(Cas 350-12-9) Usage
InChI:InChI=1/C17H18N2S2/c20-17-19(12-16-9-5-2-6-10-16)13-18(14-21-17)11-15-7-3-1-4-8-15/h1-10H,11-14H2
350-12-9 Relevant articles
Synthesis and antimicrobial activities of 2-thione-3-substituted-5-(4-carboxycyclohexyl-methyl)-tetrahydro-2H-1, 3, 5-thiadiazine derivatives
?z?elik, Azime Berna,Yilmaz, Günseli,?zkan, Semiha,Ersan, Seyhan
, p. 1059 - 1064 (2016/07/15)
(Formula Presented) In this study, 3-sub...
Exploring the structure-activity relationships of [1-(4-(4- tert-butyl-3'-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective δ-opioid receptor nonpeptide agonist ligand
Alfaro-Lopez, Josue,Okayama, Toru,Hosohata, Keiko,Davis, Peg,Porreca, Frank,Yamamura, Henry I.,Hruby, Victor J.
, p. 5359 - 5368 (2007/10/03)
SL-3111 [1-(4-tert-butyl-3'-hydroxy)benz...
Model for delivery of amines through incorporation into a tetrahydro-2H-1,3,5-thiadiazine-2-thione structure
El-Shorbagi, A-Na
, p. 11 - 16 (2007/10/02)
Phenethylamine 1a (a; n = 2) and benzyla...
New tetrahydro-1,3,5-thiadiazine-2-thiones with antimycotic, antibacterial and anthelmintic effect
Schorr,Duerckheimer,Klatt,Laemmler,Nesemann,Schrinner
, p. 1807 - 1819 (2007/10/05)
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350-12-9 Process route
-
-
75-15-0,12122-00-8
carbon disulfide
-
-
50-00-0,30525-89-4,61233-19-0
formaldehyd
-
-
100-46-9
benzylamine
-
-
350-12-9
Sulbentine
Conditions
| Conditions | Yield |
|---|---|
|
carbon disulfide; benzylamine;
With
potassium hydroxide;
In
ethanol;
at 30 - 35 ℃;
for 3h;
formaldehyd;
In
water;
Heating;
|
77.2%
|
|
Multistep reaction;
(i) MeOH, (ii) /BRN= 1209228/, H2O;
|
|
|
Multistep reaction;
(i) EtOH, (ii) /BRN= 1209228/, H2O;
|
|
|
Multistep reaction;
(i) aq. NaOH, (ii) /BRN= 1209228/;
|
|
|
formaldehyd; benzylamine;
In
ethanol; water;
at 20 ℃;
for 0.5h;
carbon disulfide;
In
ethanol; water;
for 0.333333h;
Heating;
|
-
-
50-00-0,30525-89-4,61233-19-0
formaldehyd
-
-
1950-25-0
potassium benzylcarbamodithioate
-
-
100-46-9
benzylamine
-
-
350-12-9
Sulbentine
Conditions
| Conditions | Yield |
|---|---|
|
With
phosphate buffer;
Yield given. Multistep reaction;
1.) 1 h, 2.) RT, 2 h;
|
350-12-9 Upstream products
-
75-15-0
carbon disulfide
-
50-00-0
formaldehyd
-
100-46-9
benzylamine
-
1950-25-0
potassium benzylcarbamodithioate
350-12-9 Downstream products
-
622-78-6
Benzyl isothiocyanate