- CAS 17736-20-8
- Purity 99%
3alpha,17,21-trihydroxy-5beta-pregnane-11,20-dione 21-acetate 17736-20-8 with purity >99% Low price in stock
- Molecular Formula: C23H34 O6
- Molecular Weight: 406.519
- Vapor Pressure: 9.97E-15mmHg at 25°C
- Boiling Point: 557°Cat760mmHg
- Flash Point: 187.4°C
- PSA： 100.90000
- Density: 1.228g/cm3
- LogP: 2.43230
3alpha,17,21-trihydroxy-5beta-pregnane-11,20-dione 21-acetate(Cas 17736-20-8) Usage
InChI:InChI=1/C23H34O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h14-17,20,25,28H,4-12H2,1-3H3/t14-,15-,16+,17+,20-,21+,22+,23+/m1/s1
17736-20-8 Relevant articles
C-3 GLUCOSIDURONATES OF METABOLITES OF ADRENAL STEROIDS
Mattox, Vernon R.,Goodrich, June E.,Nelson, Albert N.
, p. 23 - 34 (1982)
On treatment with methyl 2,3,4-tri-O-ace...
A novel synthesis of tetrahydrocortisone 3-glucuronide
Aisa, Haji A.,Jiang, Xiangrui,Li, Rui,Shen, Jingshan,Zhang, Suqing,Zhang, Yan
, (2022/01/19)
A new route for the synthesis of tetrahy...
Synthesis of haptens for use in immunoassay of tetrahydrocortisol, tetrahydrocortisone and their glucuronides
Hosoda,Saito,Ito,et al.
, p. 2110 - 2118 (2007/10/02)
-
17736-20-8 Process route
-
-
1499-59-8
21-acetoxy-17-hydroxy-5β-pregnane-3,11,20-trione
-
-
17736-20-8
3α,17,21-trihydroxy-5β-pregnane-11,20-dione 21-acetate
Conditions
| Conditions | Yield |
|---|---|
|
With
lithium tri-t-butoxyaluminum hydride;
In
tetrahydrofuran;
at 0 ℃;
for 2h;
Reagent/catalyst;
Solvent;
Temperature;
stereoselective reaction;
Inert atmosphere;
|
71%
|
-
-
(1S)-methyl α-D-glucopyranuronate cyclic 1,2-(hydrogen orthoacetate) 3,4-diacetate 6-ester with 21-acetoxy-3α,17-dihydroxy-5β-pregnane-11,20-dione
-
-
17736-20-8
3α,17,21-trihydroxy-5β-pregnane-11,20-dione 21-acetate
Conditions
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride; methanol;
In
benzene;
for 0.166667h;
|
51%
|
17736-20-8 Upstream products
-
641-78-1
3α,17-dihydroxy-5β-pregnane-11,20-dione
-
906336-84-3
21-acetoxy-16α,17-epoxy-3α-hydroxy-5β-pregnane-11,20-dione
-
83274-72-0
21-acetoxy-3α,17α-dihydroxy-5β-pregnane-11,20-dione 3-tert-butyldimethylsilyl ether
-
50-03-3
hydrocortisone acetate
17736-20-8 Downstream products
-
5422-85-5
21-acetoxy-4ξ-chloro-17-hydroxy-5β-pregnane-3,11,20-trione
-
1499-59-8
21-acetoxy-17-hydroxy-5β-pregnane-3,11,20-trione
-
26312-91-4
17,21-dihydroxy-11,20-dioxo-5β-pregnan-3α-yl β-D-glucopyranosiduronic acid
-
83274-72-0
21-acetoxy-3α,17α-dihydroxy-5β-pregnane-11,20-dione 3-tert-butyldimethylsilyl ether